Companies: 11,396     total market cap: $149.053 T
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SPDR S&P Biotech ETF
XBI
#275
ETF rank
$10.45 B
Marketcap
🇺🇸 US
Market
$154.89
Share price
-1.28%
Change (1 day)
40.69%
Change (1 year)
🧬 Biotech ETFs
Categories

SPDR S&P Biotech ETF - Holdings

Etf holdings as of November 6, 2026Number of holdings: 167

Full holdings list

Weight %NameTickerShares Held
2.79%
MODERNA INCMRNA1121029
1.78%
SPYRE THERAPEUTICS INCSYRE1748671
1.77%
EXELIXIS INCEXEL2606134
1.75%
BIOGEN INCBIIB721380
1.75%
AMGEN INCAMGN388550
1.73%
ABBVIE INCABBV605910
1.70%
GILEAD SCIENCES INCGILD1043745
1.67%
ORUKA THERAPEUTICS INCORKA1661382
1.66%
REGENERON PHARMACEUTICALSREGN188214
1.65%
UNITED THERAPEUTICS CORPUTHR299974
1.63%
TG THERAPEUTICS INCTGTX2781652
1.58%
NEUROCRINE BIOSCIENCES INCNBIX979860
1.56%
VERTEX PHARMACEUTICALS INCVRTX291741
1.50%
ALKERMES PLCALKS3348389
1.45%
BRIDGEBIO PHARMA INCBBIO1998129
1.44%
PTC THERAPEUTICS INCPTCT2249803
1.43%
HALOZYME THERAPEUTICS INCHALO1415524
1.43%
TWIST BIOSCIENCE CORPTWST1211106
1.42%
KYMERA THERAPEUTICS INCKYMR1100859
1.41%
INCYTE CORPINCY1206338
1.40%
NATERA INCNTRA460245
1.38%
ROIVANT SCIENCES LTDROIV3635967
1.38%
REVOLUTION MEDICINES INCRVMD732047
1.37%
CRISPR THERAPEUTICS AGCRSP2794490
1.35%
PROTAGONIST THERAPEUTICS INCPTGX1042652
1.34%
RHYTHM PHARMACEUTICALS INCRYTM1218409
1.32%
INSMED INCINSM1180271
1.29%
BIOMARIN PHARMACEUTICAL INCBMRN2360107
1.29%
KRYSTAL BIOTECH INCKRYS436746
1.28%
KODIAK SCIENCES INCKOD1318893
1.28%
VAXCYTE INCPCVX2047590
1.24%
COGENT BIOSCIENCES INCCOGT4013063
1.22%
ERASCA INCERAS8622153
1.20%
GRAIL INCGRAL1007626
1.20%
PRAXIS PRECISION MEDICINES IPRAX440249
1.20%
DIANTHUS THERAPEUTICS INCDNTH1420198
1.18%
CG ONCOLOGY INCCGON1585999
1.16%
MIRUM PHARMACEUTICALS INCMIRM1264354
1.11%
TRAVERE THERAPEUTICS INCTVTX2295634
1.09%
MADRIGAL PHARMACEUTICALS INCMDGL278088
1.08%
CYTOKINETICS INCCYTK2051308
1.05%
ARROWHEAD PHARMACEUTICALS INARWR1839771
1.05%
IONIS PHARMACEUTICALS INCIONS2713706
1.04%
CAREDX INCCDNA1359341
1.02%
IMMUNITYBIO INCIBRX1.2038757E7
0.93%
VIKING THERAPEUTICS INCVKTX3543940
0.91%
BEAM THERAPEUTICS INCBEAM3540409
0.91%
IOVANCE BIOTHERAPEUTICS INCIOVA1.1574457E7
0.91%
RELAY THERAPEUTICS INCRLAY5002936
0.90%
ALNYLAM PHARMACEUTICALS INCALNY589236
0.88%
TANGO THERAPEUTICS INCTNGX4182183
0.86%
SCHOLAR ROCK HOLDING CORPSRRK1875685
0.80%
CELCUITY INCCELC1231594
0.79%
ULTRAGENYX PHARMACEUTICAL INRARE5242871
0.79%
DYNE THERAPEUTICS INCDYN4475154
0.78%
ARCUTIS BIOTHERAPEUTICS INCARQT3107353
0.72%
VIRIDIAN THERAPEUTICS INCVRDN2567461
0.65%
IMMUNOVANT INCIMVT2167988
0.64%
PALVELLA THERAPEUTICS INCPVLA372739
0.62%
DENALI THERAPEUTICS INCDNLI3143431
0.61%
VERICEL CORPVCEL1135363
0.60%
SUMMIT THERAPEUTICS INCSMMT3740041
0.59%
RECURSION PHARMACEUTICALS ARXRX1.7089916E7
0.58%
ADMA BIOLOGICS INCADMA4664906
0.57%
DISC MEDICINE INCIRON740530
0.57%
VERACYTE INCVCYT2399150
0.55%
VERA THERAPEUTICS INCVERA1887347
0.54%
REPLIMUNE GROUP INCREPL2559733
0.54%
BIOHAVEN LTDBHVN3806037
0.53%
BIOCRYST PHARMACEUTICALS INCBCRX7089827
0.53%
HYPERLIQUID STRATEGIESPURR6165117
0.53%
SAREPTA THERAPEUTICS INCSRPT3045132
0.53%
ACADIA PHARMACEUTICALS INCACAD2543827
0.51%
ABSCI CORPABSI5089127
0.50%
AGIOS PHARMACEUTICALS INCAGIO1752689
0.50%
NOVAVAX INCNVAX4736453
0.50%
IDEAYA BIOSCIENCES INCIDYA1632352
0.49%
INTELLIA THERAPEUTICS INCNTLA4409998
0.48%
CELLDEX THERAPEUTICS INCCLDX1649413
0.48%
SELLAS LIFE SCIENCES GROUP ISLS5829404
0.47%
XENCOR INCXNCR1341556
0.44%
UNIQURE NVQURE2090156
0.42%
FIRST TRACKS BIOTHERAPEU W/ITRAX899368
0.38%
ARCUS BIOSCIENCES INCRCUS2130725
0.37%
IMMUNOME INCIMNM2007551
0.37%
NEKTAR THERAPEUTICSNKTR1003349
0.35%
STOKE THERAPEUTICS INCSTOK1349442
0.34%
NURIX THERAPEUTICS INCNRIX2255850
0.31%
VIR BIOTECHNOLOGY INCVIR2619545
0.30%
ANAPTYSBIO INCANAB658813
0.30%
ZENAS BIOPHARMA INCZBIO1067590
0.28%
MANNKIND CORPMNKD7372689
0.28%
INHIBRX BIOSCIENCES INCINBX334169
0.26%
JADE BIOSCIENCES INCJBIO1764140
0.26%
PRECIGEN INCPGEN5837646
0.25%
HEMAB THERAPEUTICS HOLDINGSCOAG529708
0.25%
ANNEXON INCANNX6016349
0.25%
TYRA BIOSCIENCES INCTYRA1188155
0.24%
SYNDAX PHARMACEUTICALS INCSNDX2620766
0.23%
MINERALYS THERAPEUTICS INCMLYS1511064
0.22%
MONTE ROSA THERAPEUTICS INCGLUE2166247
0.22%
TAYSHA GENE THERAPIES INCTSHA5287078
0.22%
VOR BIOPHARMA INCVOR1123126
0.21%
ORIC PHARMACEUTICALS INCORIC2487371
0.21%
ARDELYX INCARDX7482480
0.20%
JANUX THERAPEUTICS INCJANX1167093
0.19%
CORVUS PHARMACEUTICALS INCCRVS1863892
0.19%
CANDEL THERAPEUTICS INCCADL2242477
0.19%
VERASTEM INCVSTM2312041
0.19%
RIGEL PHARMACEUTICALS INCRIGL487453
0.19%
KURA ONCOLOGY INCKURA2614734
0.18%
GERON CORPGERN1.8576752E7
0.17%
DAMORA THERAPEUTICS INCDMRA744569
0.17%
PRIME MEDICINE INCPRME3722500
0.17%
MYRIAD GENETICS INCMYGN2914470
0.17%
IMMIX BIOPHARMA INCIMMX2116851
0.16%
CAPRICOR THERAPEUTICS INCCAPR1830902
0.16%
KAILERA THERAPEUTICS INCKLRA1257119
0.16%
OLEMA PHARMACEUTICALS INCOLMA2206991
0.15%
SAVARA INCSVRA3275454
0.15%
REGENXBIO INCRGNX2038297
0.15%
IRONWOOD PHARMACEUTICALS INCIRWD3416680
0.14%
4D MOLECULAR THERAPEUTICS INFDMT1208764
0.14%
ACHIEVE LIFE SCIENCES INCACHV2156058
0.14%
CULLINAN THERAPEUTICS INCCGEM1261694
0.13%
SANA BIOTECHNOLOGY INCSANA5619546
0.13%
ARRIVENT BIOPHARMA INCAVBP945093
0.13%
SAGIMET BIOSCIENCES INC ASGMT1299676
0.12%
SOLID BIOSCIENCES INCSLDB1800443
0.11%
CYTOMX THERAPEUTICS INCCTMX5223214
0.11%
CLIMB BIO INCCLYM1107243
0.11%
EDITAS MEDICINE INCEDIT4351438
0.10%
ARBUTUS BIOPHARMA CORPABUS2873472
0.10%
AVALO THERAPEUTICS INCAVTX1513025
0.10%
OCUGEN INCOCGN1.1142389E7
0.10%
MONOPAR THERAPEUTICS INCMNPR141238
0.10%
EMERGENT BIOSOLUTIONS INCEBS1662255
0.10%
ALLOGENE THERAPEUTICS INCALLO9524916
0.10%
DESIGN THERAPEUTICS INCDSGN961551
0.10%
BICARA THERAPEUTICS INCBCAX1123683
0.09%
ALTIMMUNE INCALT4578953
0.09%
SHATTUCK LABS INCSTTK1885228
0.08%
AKTIS ONCOLOGY INCAKTS524616
0.08%
OVID THERAPEUTICS INCOVID2855671
0.07%
CONTRA METSERA INC-1530714
0.07%
PROTHENA CORP PLCPRTA930267
0.07%
VANDA PHARMACEUTICALS INCVNDA1840350
0.07%
NEUROGENE INCNGNE274737
0.06%
CABALETTA BIO INCCABA5086787
0.06%
ASSEMBLY BIOSCIENCES INCASMB310436
0.06%
AURA BIOSCIENCES INCAURA965205
0.06%
ARS PHARMACEUTICALS INCSPRY2238515
0.06%
MIMEDX GROUP INCMDXG1851358
0.05%
FAETH THERAPEUTICS INCFTH220572
0.05%
LEXEO THERAPEUTICS INCLXEO1627662
0.05%
CRESCENT BIOPHARMA INCCBIO342088
0.04%
COMPASS THERAPEUTICS INCCMPX4946748
0.02%
SSI US GOV MONEY MARKET CLASS-2441525.910
0.01%
BRIDGEBIO ONCOLOGY THERAPEUTBBOT677459
0.01%
CONTRA AKERO THERAPEUT-2033975
0.01%
CONTRA INHIBRX INC-1645973
0.01%
CONTRA MIRATI THERAPEU-1369552
0.01%
CONTRA VERVE THERAPEUT-900273
0.00%
CONTRA BLUEPRINT MEDIC-756469
0.00%
US DOLLAR-24108.860
0.00%
OMNIAB INC 12.5 EARNOUT2200963D161959
0.00%
OMNIAB INC 15.00 EARNOUT2200964D161959

What is the market capitalization of a company?

The market capitalization sometimes referred as Marketcap, is the value of a publicly listed company.
In most cases it can be easily calculated by multiplying the share price with the amount of outstanding shares.

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